Simple test could help clinicians spot abnormal blood levels of dopamine in patients

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Altered levels of the neurotransmitter dopamine are evident in several conditions, such as Parkinson’s disease and depression. In research published in ChemistrySelectresearchers describe a fast, sensitive and simple test to determine dopamine levels in biological fluids. The method could help clinicians detect abnormal blood levels of dopamine in patients, potentially enabling earlier detection of the disease.

The method is based on what are called carbon quantum dots, a type of carbon nanomaterial with photoluminescence properties, and an ionic liquid, which consists of various mineral anions and organic cations that exist in liquid form at room temperature.

“The proposed electrochemical sensor could represent an exceptional advance in dopamine sensing and pave the way for the molecular diagnosis of neurological diseases,” the authors wrote.

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Magazine reference:

Nazari, Z., et al. (2023) An electrochemical sensor based on carbon quantum dots and ionic liquids for selective detection of dopamine. ChemistrySelect. doi.org/10.1002/slct.202203630.

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